QuickView for forkhead box O1;jsessionid=E949AFF123C64812557941F4154EBC0C;jsessionid=2CC10CBBAD8F564672A08A0218E1C0C2 (gene)
- Gene Symbol:
- Foxo1
Rattus norvegicus - Full name:
- forkhead box O1
- Synonyms:
- Fkhr, Foxo1a, forkhead box protein O1, Forkhead box protein O1A, Forkhead in rhabdomyosarcoma, forkhead box O1A (rhabdomyosarcoma)
- Genomic Location:
- Chr 2: 141126993-141204031
- Description:
-
mediates effects of insulin on glucose-6-phosphatase gene expression
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
AACTTT_UNKNOWN , ACTWSNACTNY_UNKNOWN , NKX25_01 , FOXO1_01 , FOXO1_02 , FOXO4_02 , FOXO3_01 , GNCF_01 , CTTTAAR_UNKNOWN , AP2_Q3
GO Molecular Function
sequence-specific DNA binding | beta-catenin binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | protein phosphatase 2A binding | enzyme binding | nucleic acid binding | transcription coactivator binding | ubiquitin-like protein ligase binding | DNA binding | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | organic cyclic compound binding | protein binding | DNA-binding transcription factor activity | protein phosphatase binding | transcription factor binding | ubiquitin protein ligase binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | phosphatase binding | transcription cofactor binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | response to extracellular stimulus | regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter | negative regulation of phosphorylation | cellular response to increased oxygen levels | regulation of muscle system process | positive regulation of macromolecule biosynthetic process | response to nutrient levels | negative regulation of MAPK cascade | positive regulation of apoptotic process | regulation of carbohydrate metabolic process | regulation of programmed cell death | regulation of autophagy | response to hormone | cellular response to hyperoxia | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | response to dexamethasone | negative regulation of RNA biosynthetic process | negative regulation of fat cell differentiation | cellular response to extracellular stimulus | positive regulation of protein catabolic process | response to drug | negative regulation of protein phosphorylation | regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter | glucose homeostasis | response to antibiotic | negative regulation of stress-activated protein kinase signaling cascade | positive regulation of cellular biosynthetic process | cellular process | odontogenesis | negative regulation of signaling | cellular response to nitric oxide | negative regulation of nucleic acid-templated transcription | stem cell population maintenance | negative regulation of apoptotic process | tooth mineralization | cellular response to starvation | positive regulation of nitrogen compound metabolic process | response to inorganic substance | regulation of canonical Wnt signaling pathway | negative regulation of cellular metabolic process | response to peptide hormone | tissue development | regulation of fat cell differentiation | regulation of cell differentiation | response to hydrogen peroxide | negative regulation of muscle hypertrophy | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | response to stimulus | vasculature development | positive regulation of protein metabolic process | cellular response to xenobiotic stimulus | response to stress | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | response to peptide | response to starvation | programmed cell death | cellular response to inorganic substance | cardiovascular system development | cellular nitrogen compound metabolic process | cellular response to toxic substance | cellular response to organic cyclic compound | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | blood vessel development | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | response to nitrogen compound | apoptotic process | cellular response to hormone stimulus | system development | cellular response to nutrient levels | response to oxygen levels | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | cellular response to antibiotic | multicellular organism development | cellular response to peptide hormone stimulus | regulation of MAPK cascade | cellular response to DNA damage stimulus | cellular response to insulin stimulus | cellular response to oxidative stress | regulation of phosphorylation | positive regulation of gluconeogenesis | regulation of gene expression | response to ketone | cellular response to stress | response to lipid | cellular response to peptide | insulin receptor signaling pathway | positive regulation of cellular metabolic process | animal organ morphogenesis | negative regulation of cardiac muscle hypertrophy | amelogenesis | cellular response to oxygen levels | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | response to corticosteroid | regulation of transcription by RNA polymerase II | response to oxidative stress | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | cellular response to glucocorticoid stimulus | response to hyperoxia | negative regulation of stress-activated MAPK cascade | response to toxic substance | response to xenobiotic stimulus | cellular response to corticosteroid stimulus | autophagy | cellular response to drug | regulation of cardiac muscle hypertrophy in response to stress | cell communication | regulation of cellular metabolic process | odontogenesis of dentin-containing tooth | regulation of protein metabolic process | homeostatic process | regulation of protein phosphorylation | regulation of RNA metabolic process | neuronal stem cell population maintenance | negative regulation of cardiac muscle hypertrophy in response to stress | regulation of cardiac muscle hypertrophy | DNA-binding transcription factor activity | response to organic substance | cellular response to reactive nitrogen species | response to antineoplastic agent | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | response to insulin | anatomical structure development | cell surface receptor signaling pathway | regulation of glucose metabolic process | regulation of neural precursor cell proliferation | metabolic process | positive regulation of glucose metabolic process | regulation of protein catabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | cellular response to hydrogen peroxide | chemical homeostasis | positive regulation of cell death | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | cellular response to reactive oxygen species | organic substance metabolic process | maintenance of cell number | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | response to reactive oxygen species | negative regulation of cellular protein metabolic process | gene expression | positive regulation of programmed cell death | regulation of Wnt signaling pathway | regulation of phosphate metabolic process | biomineral tissue development | cellular response to steroid hormone stimulus | negative regulation of cardiac muscle adaptation | positive regulation of autophagy | transcription, DNA-templated | cellular response to dexamethasone stimulus | anatomical structure formation involved in morphogenesis | negative regulation of protein metabolic process | positive regulation of carbohydrate metabolic process | regulation of stress-activated MAPK cascade | regulation of cell communication | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | regulation of developmental process | developmental process | negative regulation of canonical Wnt signaling pathway | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | regulation of reactive oxygen species metabolic process | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | regulation of gluconeogenesis | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | negative regulation of Wnt signaling pathway | response to fluoride | cellular metabolic process | cellular response to organic substance | enamel mineralization | regulation of cell death | response to nitric oxide | response to steroid hormone | negative regulation of cell death | circulatory system development | carbohydrate homeostasis | negative regulation of cell differentiation | signal transduction | regulation of signaling | positive regulation of gene expression | response to glucocorticoid | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | cytosol | intracellular
